NFL Picks Week 15

The NFL Season heads into the fifteenth stanza. NFL Week 15 odds suggest that our picks are in store for a wild time. Also, some games, like the Sunday night football matchup between the Giants and Commanders, should have significant playoff repercussions.

As opposed to the Sunday night football game, the Monday game is a snorer. But Los Angeles Rams versus Green Bay Packers does boast a decent quarterback duel.

Bye weeks are over. Let’s get down to business for a full slate of gridiron glory, including three Saturday games, which all air on the NFL Network.  

NFL Week 15 Odds Thursday, Dec. 15

San Francisco 49ers -3.5 at Seattle Seahawks – 8:15 p.m. ET

Action on sidebar NFL odds, like the San Francisco 49ers -6, suggests SF runs away with this. Since a loss to the Kansas City Chiefs, the Niners have rolled.

There’s no reason to believe San Francisco doesn’t dominate on Thursday night. Expect a similar game to the win over the Miami Dolphins, where SF contains Geno Smith and his mates the same way they did Tua and his bevy of receivers.

Even though Deebo Samuel suffered an ankle injury in the last, San Francisco rolls.  

NFL Week 15 Odds Saturday, Dec. 17

Indianapolis Colts at Minnesota Vikings -4.5 – 1:00 p.m ET

Not many handicappers are paying attention to Colts versus Vikings, which could be a mistake. Since upsetting the Bills, Minnesota has played okay but not great football.

Indianapolis could be catching Minnesota at the right time. But this happens on Minnesota’s field, and Indy is a horrible 2-5 ATS on the road. Lay the points.   

Baltimore Ravens at Cleveland Browns -2.5 – 4:30 p.m ET

The Baltimore Ravens might have to start third string quarterback rookie Anthony Brown. The opening line suggested Tyler Huntley or Lamar Jackson might play.

But since then, more info has come out. If Brown gets the start, Cleveland should offer way more points than 2.5. So if you like Cleveland, go with the home squad. Do we like the Browns? Yep.    

Miami Dolphins at Buffalo Bills -7.5 – 8:15 p.m ET

Tua and the Dolphins have struggled in their last couple of games because they have zero running game. The point spread in this matchup suggests another ugly Fins loss just like the defeat to the Los Angeles Chargers.

It doesn’t help that the Bills dominated the New England Patriots two games ago. In addition, Tagovailoa’s top target, Tyreek Hill, suffered an injury in the Dolphins’ last.

Some believe Hill’s injury is a high ankle sprain. Without Hill, it will be difficult for the Fins to keep pace. Here’s another where laying the points makes sense. So much so that Buffalo is a best bet.   

NFL Week 15 PICKS – Sunday, Dec. 18

Detroit Lions -1 at New York Jets – 1:00 p.m ET

The New York Jets lost to the Buffalo Bills in their last. The Detroit Lions almost pulled off the win over the Buffalo Bills on Thanksgiving Day.

The Jets boast one of the league’s top defenses. So the opening line could be undervaluing NYJ.

Both teams are throwing down for a playoff spot. Losing to the Bills is no disgrace. So we can’t use that as a barometer. Since New York is at home, the Jets are the play in the first of our picks for NFL week 15.    

Kansas City Chiefs -14 at Houston Texans – 1:00 p.m ET

Kansas City is winning, but the Chiefs remain a terrible cover team. Also, this is a massive opening line. 14 feels like way too many points.  

Also, Houston almost pulled off the upset against the Dallas Cowboys. So this is one of the week’s more interesting point spreads.

In addition, Patrick Mahomes heads to Houston off a three interceptions game versus the Broncos. This matchup is a sneaky challenging game for Mahomes and the Chiefs. Taking the points on the Texans makes sense.

Pittsburgh Steelers at Carolina Panthers -2.5 – 1:00 p.m ET

Once again, Steelers rookie quarterback Kenny Pickett is in concussion protocol.

The early bets on this contest moved the Panthers from -1.5 to -2.5. The points movement from the opening line makes the NFL odds on the Panthers in this matchup more than fair. Go with the Panthers in yet another best bet play.    

Philadelphia Eagles -9 at Chicago Bears – 1:00 p.m ET

The Philadelphia Eagles are rolling, winning two straight. In their last, the Philly Birds blasted the New York Giants 48-22.

Early bets suggest the Eagles dominate. The opening line was Philly -7.5. A lot of money has already gone to Philadelphia.

One of the reasons so much money has landed on Philly is because a victory ends the Dallas Cowboys’ hopes of catching the Eagles in the NFC East.

The NFL odds are more than fair. The Eagles win and cover. 

Atlanta Falcons at New Orleans Saints -4 – 1:00 p.m ET

N’Awlins had their bye week, which gives the Falcons an edge. The Saints don’t always perform well after a bye.

Not only that, but the Saints lost to rival Tampa Bay in their last. The Falcons will go with rookie Desmond Ridder in this matchup, which is interesting because the ATL can still catch the Buccaneers for the NFC South title.

Going with Ridder might not be a wise move. Saints are the play.    

Dallas Cowboys -4.5 at Jacksonville Jaguars – 1:00 p.m ET

Dallas struggled big time against Houston as a -17 chalk. On Sunday, the Boys battle Trevor Lawrence and the Jaguars on the road.

Jacksonville may have turned the corner with their week 14 NFL victory, a 36-22 win versus the rival Titans. The Jags may not win, but Dallas shouldn’t grab the W by more than 3 points.

Arizona Cardinals at Denver Broncos -2.5 – 4:05 p.m ET

The opening line doesn’t take into account Kyler Murray’s injury. The Arizona Cardinals starting quarterback suffered a torn ACL that sent him to injured reserve.

For Denver, quarterback Russell Wilson played his best game in a Bronco uniform in the home team’s last. Russell should continue to play well, which means the Cards lose by more than the points line suggests.   

New England Patriots -1.5 at Las Vegas Raiders – 4:05 p.m ET

During New England’s Monday night victory over the Cardinals, wide receiver Devante Parker should have gone into the NFL’s concussion protocol. But although the concussion spotters missed Devante’s wobbliness, Parker should play against Las Vegas on Sunday.

But the game happens in Las Vegas, where Derek Carr and the Raiders often play well. Also, Raiders head coach Josh McDaniels goes against his mentor, the greatest NFL coach of all time, Bill Belichick. Josh won’t beat Bill.

Cincinnati Bengals -3.5 at Tampa Bay Buccaneers – 4:25 p.m ET

Tom Brady and the Tampa Bay Buccaneers host Joe Burrow and the Cincinnati Bengals a week after falling 35-7 to the 49ers. But before losing to SF, the Bucs had gotten past the rival New Orleans Saints 17-16.

So expect Tampa Bay to provide a strong showing. Still, the red hot Bengals have dominated winning five straight games. Also, the NFC South is a disaster.

So Tampa isn’t playing great football and, on Sunday, faces one of the hottest teams in the league. Even though Tee Higgins is out, Cincinnati wins and covers. This game has best bet written all over it.  

Tennessee Titans at Los Angeles Chargers -3 – 4:25 p.m ET

Los Angeles broke a two NFL game losing streak in week 14. Things don’t get any easier because the Chargers’ porous rush defense faces the great Derrick Henry in this matchup.

But the Titans, although a good team, need to play better. The problem? Injuries. The Titans’ offensive line is in shambles, and the secondary is a disaster. The Chargers win and cover in this contest between a pair of teams in the playoff hunt. 

New York Giants at Washington Commanders -4.5 – 8:20 p.m. ET

This NFL Sunday Night Football matchup pits two playoff hunt teams against each other. Neither team is going to catch the 1-loss Philadelphia Eagles.  

The New York Giants are desperate for a win. The G-men struggled big time versus the Eagles in their last.

But NYG is attracting the early money. Washington might be the play if the line was D.C. -3, but the Giants get the nod at +4.5.  

NFL Week 15 PICKS – Monday, Dec. 19

Los Angeles Rams at Green Bay Packers -7 – 8:15 p.m. ET

The Monday night football contest between the Rams and Packers should have zero effect on the NFC Playoff race. However, Baker Mayfield’s performance in the Rams’ last game makes this must-watch television.  

Green Bay offers underlay odds. Look for free bets on the Rams if possible because beating the Packers at Lambeau is never easy.

Monday’s game is a must-watch, but it might be something other than a must-play. Make sure to do your homework. We’ve done our early homework, and we like Los Angeles. We like L.A. so much, they’re a best bet.